Holding(s) in Company

Aortech International PLC 07 February 2008 TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached (ii): AorTech International plc 2. Reason for the notification (please state Yes/No): ( ) An acquisition or disposal of voting rights: ( Yes ) An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached: ( ) An event changing the breakdown of voting rights: ( ) Other (please specify): ( ) 3. Full name of person(s) subject to the notification obligation (iii): Deutsche Bank AG 4. Full name of shareholder(s) (if different from 3.) (iv): 5. Date of the transaction (and date on which the threshold is crossed or reached if different) (v): 05/02/2008 6. Date on which issuer notified: 06/02/2008 7. Threshold(s) that is/are crossed or reached: 7 - 3% 8. Notified details: A: Voting rights attached to shares Class/type of shares if possible Situation previous to the Triggering transaction (vi) using the ISIN CODE Number of shares Number of voting Rights (viii) GB0033360586 340,540 340,898 Resulting situation after the triggering transaction (vii) Class/type of shares if Number of shares Number of voting rights (ix) % of voting rights possible using the ISIN CODE Direct Direct (x) Indirect (xi) Direct Indirect GB0033360586 Below 3% Below 3% - Below 3% - B: Financial Instruments Resulting situation after the triggering transaction (xii) Type of Expiration Date (xiii) Exercise/Conversion Period/ Number of voting rights that % of voting rights financial Date (xiv) may be acquired if the instrument instrument is exercised/ converted. N/A N/A N/A N/A N/A Total (A+B) Number of voting rights % of voting rights Below 3% Below 3% 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable (xv): n/a Proxy Voting: 10. Name of the proxy holder: n/a 11. Number of voting rights proxy holder will cease to hold: n/a 12. Date on which proxy holder will cease to hold voting rights: n/a 13. Additional information: n/a 14. Contact name: David Lindsay / Andrew Anderson 15. Contact number: 0207 545 8533/8532 This information is provided by RNS The company news service from the London Stock Exchange
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