Holding(s) in Company

Aortech International PLC
10 March 2008

TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES



1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached (ii):

AorTech International plc



2. Reason for the notification (please state Yes/No): (    )

An acquisition or disposal of voting rights: (Yes )

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached: (    )

An event changing the breakdown of voting rights: (    )

     Other (please specify): (   )


3. Full name of person(s) subject to the notification obligation (iii):

    Credit Agricole Cheuvreux International Ltd

4. Full name of shareholder(s) (if different from 3.) (iv):



Credit Agricole Cheuvreux International Ltd



5. Date of the transaction (and date on which the threshold is crossed or
reached if different) (v):

     4 March 2008

6. Date on which issuer notified:



6 March 2008



7. Threshold(s) that is/are crossed or reached:


     7%


8. Notified details:





A: Voting rights attached to shares


Class/type of shares if possible                    Situation previous to the Triggering transaction (vi)
using the ISIN CODE
                                                             Number of shares             Number of voting Rights (viii)
GB0033360586                                                     Less than 3%                               Less than 3%



Resulting situation after the triggering transaction (vii)


Class/type of shares if          Number of shares        Number of voting rights (ix)       % of voting rights
possible using the ISIN CODE
                                                           Direct (x)     Indirect (xi)          Direct    Indirect
GB0033360586                           372,500             372,500                 -             7.71%           -

B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of          Expiration Date (xiii)  Exercise/Conversion Period/ Number of voting rights that  % of voting rights
financial                                Date (xiv)                  may be acquired if the
instrument                                                           instrument is exercised/
                                                                     converted.
N/A                  N/A                 N/A                           N/A                    N/A



Total (A+B)
               Number of voting rights                   % of voting rights
                      372,500                                7.71%



9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):

SAS Rue La Boetie
Credit Agricole SA
Calyon SA
Credit Agricole Cheuvreux SA    372,500 (7.71%)



Proxy Voting:


10. Name of the proxy holder:



11. Number of voting rights proxy holder will cease to hold:



12. Date on which proxy holder will cease to hold voting rights:



13. Additional information:



14. Contact name:



Gabrielle Burne



15. Contact number:



020 7214 6037





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