Holding(s) in Company

Aortech International PLC
28 February 2008


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
   voting rights are attached (ii):

   AorTech International plc

2. Reason for the notification (please state Yes/No): ( )

   An acquisition or disposal of voting rights: (Yes )
   An acquisition or disposal of financial instruments which may result in the
   acquisition of shares already issued to which voting rights are attached: ( )
   An event changing the breakdown of voting rights: ( )
   Other (please specify): ( )

3. Full name of person(s) subject to the notification obligation (iii):

   Credit Agricole Cheuvreux International Ltd

4. Full name of shareholder(s) (if different from 3.) (iv):

   Credit Agricole Cheuvreux International Ltd

5. Date of the transaction (and date on which the threshold is crossed or
   reached if different) (v):

   25 February 2008

6. Date on which issuer notified:

   27 February 2008

7. Threshold(s) that is/are crossed or reached:

   Less than 3%

8. Notified details:



A: Voting rights attached to shares

Class/type of shares Situation previous to the Triggering transaction
if possible using                          (vi)
the ISIN CODE
                      Number of shares  Number of voting Rights (viii)
GB0033360586                   372,500                         372,500


Resulting situation after the triggering transaction (vii)

Class/type of       Number of      Number of voting    % of voting rights
shares if            shares           rights (ix)
possible using
the ISIN CODE
                                    Direct    Indirect     Direct Indirect
                                       (x)        (xi)
GB0033360586        Less than 3%

B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of     Expiration Date  Exercise/Conversion Number of voting     % of voting
financial   (xiii)           Period/Date (xiv)   rights that may be   rights
instrument                                       acquired if the
                                                 instrument is
                                                 exercised/
                                                 converted.
N/A         N/A              N/A                 N/A                  N/A


Total (A+B)
 Number of voting rights  % of voting rights
                                Less than 3%


9. Chain of controlled undertakings through which the voting rights and/or the
   financial instruments are effectively held, if applicable (xv):

   SAS Rue La Boetie
   Credit Agricole SA
   Calyon SA
   Credit Agricole Cheuvreux SA Less than 3%


Proxy Voting:

10. Name of the proxy holder:


11. Number of voting rights proxy holder will cease to hold:


12. Date on which proxy holder will cease to hold voting rights:


13. Additional information:


14. Contact name:

    Gabrielle Burne

15. Contact number:

    020 7214 6037

Annex to Notification Of Major Interests In Shares (xvi)


A: Identity of the person or legal entity subject to the notification obligation


Full name (including legal form for legal entities):

Credit Agricole SA

Contact address (registered office for legal entities):

Broadwalk House, 5 Appold Street, London EC2A 2DA

Phone number:

020 7214 6037

Other useful information (at least legal representative for legal persons):



B: Identity of the notifier, if applicable (xvii)


Full name:

Barbara Hall

Contact address:

As above

Phone number:

As above

Other useful information (e.g. functional relationship with the person or legal
entity subject to the notification obligation)

n/a




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