Holding(s) in Company

Aortech International PLC
10 February 2004

AorTech International plc ('the Company') announces that it received
notification today from ISIS Asset Management plc that as a result of sales
totalling 193,884 ordinary shares of £2.50 each in the capital of the Company ('
Shares') and a purchase of 193,884 Shares, the following fund management
companies in the Friends Provident group are interested in the Shares referred
to below through client holdings:



ISIS Asset Management plc is interested in the following Shares:


No. of Shares                                               %
768,296                                                     20.164



Such interest includes the material interests of the clients of ISIS Asset
Management plc referred to below:


Name of Client                       No. of Shares        %             Name of Registered Holder
Baronsmead VCT2                      16,234               0.426         Chase Nominees Ltd
Baronsmead VCT Plc                   12,734               0.334         Chase Nominees Ltd
The AIM VCT Trust                    50,980               1.338         Chase Nominees Ltd
Active Capital Trust                 680,157              17.851        Chase Nominees Ltd



Such interest also includes the interest of Friends Provident Unit Managers
which is also a member of the Friends Provident group as referred to below:


Name of Client                       No. of Shares        %             Name of Registered Holder

ISIS INV Funds ICVC III AIM Growth   7,500                0.197         Chase Nominees Ltd
Fund

ISIS Investment Funds ICVC UK Equity 691                  0.018         Chase Nominees Ltd
Fund



In addition, ISIS Asset Management plc, as the holding company of the company(s)
referred to in the paragraph(s) above is also interested in those Shares.
Furthermore, Friends Provident Life Office, as the holding company of ISIS Asset
Management plc is also interested in the Shares referred to above.




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