Holding(s) in Company

Aortech International PLC
2 June 2003



AorTech International plc ('the Company') announces that it received
notification on Friday 30 May 2003 from ISIS Asset Management plc that ISIS
Asset Management plc has a revised notifiable interest in 6,382,986 Ordinary
Shares in the Company representing approximately 16.75% of the issued ordinary
share capital.

Such interest includes the material interests of the clients of Friends Ivory &
Sime plc referred to below:

Name of Client                                No. of Shares          %         Name of Registered Holder
Baronsmead VCT2                               162,341                0.43      Chase Nominees Ltd
Baronsmead VCT Plc                            127,341                0.33      Chase Nominees Ltd
The AIM Trust Plc                             2,113,409              5.54      Chase Nominees Ltd
The AIM VCT Trust                             509,806                1.34      Chase Nominees Ltd
3PC Investment Trust                          1,297,872              3.41      Chase Nominees Ltd


Such interest also includes the interest of Friends Provident Asset Management
which is also a member of the Friends Provident group as referred to below:

Name of Client                                No. of Shares          %         Name of Registered Holder
ISIS ICVC Aim Growth Fund                     75,000                 0.20      Citifriends
ISIS ICVC UK Smaller Markets Fund             167,524                0.44      Citifriends


Such interest includes the material interest of the clients of Friends Provident
Unit Managers referred to below:

Name of Client                                No. of Shares          %         Name of Registered Holder
FP UK Equity Trust                            93,831                 0.25      Citifriends
UK Mid/Smaller Companies                      1,672,452              4.39      Citifriends


Such interest includes the material interest of the client of Friends Ivory &
Sime Managed Pension Funds referred to below:

Name of Client                                No. of Shares          %         Name of Registered Holder
ISISMPF UK Smaller Companies                  163,410                0.42      Citifriends


In addition, Friends Ivory & Sime plc, as the holding company of the company(s)
referred to in the paragraph(s) above is also interested in those Shares.
Furthermore, Friends Provident Life Office, as the holding company of Friends
Ivory & Sime plc is also interested in the Shares referred to above.






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