Holding(s) in Company

ReNeuron Group plc
08 December 2006


             NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF LISTED COMPANY

     RENEURON GROUP PLC

2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     TOSCAFIELD LIMITED

3)   Please state whether notification indicates that it is 
     regarding the holding of the shareholder named in 2 above;
     in respect of a non-beneficial interest; or in the case of an
     individual holder if it is a holding of that person's spouse
     or children under the age of 18

     PERSON NAMED IN 2.

4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.

     NOT APPLICABLE

5)   Number of shares/amount of stock acquired.

     NOT DISCLOSED

6)   Percentage of issued Class (any treasury shares held by the
     listed company should not be taken into account when
     calculating percentage)

     NOT DISCLOSED

7)   Number of shares/amount of stock disposed

     NOT DISCLOSED

8)   Percentage of issued Class (any treasury shares held by the
     listed company should not be taken into account when
     calculating percentage)

     NOT DISCLOSED

9)   Class of security

     ORDINARY SHARES

10)  Date of transaction

     NOT DISCLOSED

11)  Date listed company informed

     8 DECEMBER 2006

12)  Total holding following this notification

     15,050,000 SHARES
               
13)  Total percentage holding of issued class following this notification
     (any treasury shares held by the listed company should not be taken
     into account when calculating percentage)

     15.12%

14)  Any additional information



15)  Name of contact and telephone number for queries

     MICHAEL HUNT, CEO -

16)  Name and signature of duly authorised officer of the listed company
     responsible for making this notification

     MICHAEL HUNT

     Date of Notification     8 DECEMBER 2006



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