Holding(s) in Company

ReNeuron Group plc
05 October 2005

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1.   Name of company

      ReNeuron Group PLC

2.   Name of shareholder having a major interest

     Toscafield Limited

3.   Please state whether notification indicates that it is in respect of 
     holding of the shareholder named in 2 above or in respect of a non-
     beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18.

     As above

4.   Name of the registered holder(s) and, if more than one holder, the number 
     of shares held by each of them

     No stated

5.   Number of shares/amount of stock acquired

     Not stated

6.   Percentage of issued class

     Not stated

7.   Number of shares/amount of stock disposed

     Not stated

8.   Percentage of issued class

     Not stated

9.   Class of security

     Ordinary shares of 10p each

10.  Date of transaction

     Not stated

11.  Date company informed

     4 October 2005

12.  Total holding following this notification

     7,600,000

13.  Total percentage holding of issued class following this notification

     8.12%

14.  Any additional information



15.  Name of contact and telephone number for queries

     Michael Hunt, Chief Executive Officer         [phone]

16.  Name and signature of authorised company official responsible for making 
     this notification.

     Michael Hunt, Chief Executive Officer


Date of notification 5 October 2005




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