Director/PDMR Shareholding

ReNeuron Group plc
07 December 2006


NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL
RESPONSIBILITY OR CONNECTED PERSONS


This form is intended for use by an issuer to make a RIS notification required
by DR 3.1.4R(1).


(1)  An issuer making a notification in respect of a transaction relating to 
     the shares or debentures of the issuer should complete boxes 1 to 16, 23 
     and 24.

(2)  An issuer making a notification in respect of a derivative relating the 
     shares of the issuer should complete boxes 1 to 4, 6, 8,13, 14, 16, 23 and
     24.



(3)  An issuer making a notification in respect of options granted to a
     director/person discharging managerial responsibilities should complete 
     boxes 1 to 3 and 17 to 24.

(4)  An issuer making a notification in respect of a financial instrument
     relating to the shares of the issuer (other than a debenture) should 
     complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24.


Please complete all relevant boxes should in block capital letters.


1.   Name of the issuer                               2.   State whether the notification relates to (i) a
                                                           transaction notified in accordance with DR
                                                           3.1.4R(1)(a); or


     ReNeuron Group plc                                    (ii) DR 3.1.4(R)(1)(b) a disclosure made in
                                                           accordance with section 324 (as extended by
                                                           section 328) of the Companies Act 1985;
                                                           or


                                                           (iii) both (i) and (ii)


                                                           Notification under (ii) above.


3.   Name of person discharging managerial            4.   State whether notification relates to a person
     responsibilities/director                             connected with a person discharging managerial
                                                           responsibilities/director named in 3
                                                           and identify the connected person
     Michael Hunt, Director


                                                           N/A


5.   Indicate whether the notification is in respect  6.   Description of shares (including class),
     of a holding of the person referred to in 3 or 4      debentures or derivatives or financial
     above or in respect of a non-beneficial interest      instruments relating to shares
     1
                                                           


     Beneficial Interest
                                                           Ordinary Shares

7.   Name of registered shareholders(s) and, if more  8.   State the nature of the transaction
     than one, the number of shares held by each of
     them

                                                           Purchase

     Michael Hunt


9.   Number of shares, debentures or financial        10.  Percentage of issued class acquired (treasury
     instruments relating to shares acquired               shares of that class should not be taken into
                                                           account when calculating percentage)


     51,500 shares
                                                           0.05%


11.  Number of shares, debentures or financial        12.  Percentage of issued class disposed (treasury
     instruments relating to  shares disposed              shares of that class should not be taken into
                                                           account when calculating percentage)


     N/A
                                                           N/A


13.  Price per share or value of transaction          14.  Date and place of transaction



     19.5p per share                                       6 December 2006, England


15.  Total holding following notification and total   16.  Date issuer informed of transaction
     percentage holding following notification (any
     treasury shares should not be taken into account
     when calculating percentage)
                                                           6 December 2006


     174,613 shares





If a person discharging managerial responsibilities has been granted options by
the issuer complete the following boxes


17.  Date of grant                                    18.  Period during which or date on which it can be
                                                           exercised


19.  Total amount paid (if any) for grant of the      20.  Description of shares or debentures involved
     option                                                (class and number)


21.  Exercise price (if fixed at time of grant) or    22.  Total number of shares or debentures over which
     indication that price is to be fixed at the time      options held following notification
     of exercise


23.  Any additional information                       24.  Name of contact and telephone number for queries




Name and signature of duly authorised officer of issuer responsible for making notification





__________________________________________________________





Date of notification _____________________________________








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