Distribution Announcement

Provexis PLC
23 January 2006


                                  PROVEXIS PLC
                         ('Provexis' or the 'Company')

       Significant Increase in Number of Distribution Outlets for SircoTM

Provexis, the nutraceutical company that develops scientifically-proven
functional and medical foods, announces a significant increase in the number of
distribution outlets for its SircoTM heart health juice drink, under the terms
of its most recent distribution agreement with a market leading supermarket
chain.

Further to the Company's announcement of 9 January 2006 detailing its third
distribution agreement, SircoTM will now be available in 550 of this retailer's
stores from 30 January 2006, representing an increase of 350 outlets. Sirco is
now available in 211 Sainsbury's stores and will be available in 123 Waitrose
stores from 23 January 2006. This will bring the total UK distribution base for
Sirco to 884 stores by the end of January 2006.

SircoTM is the first heart health product to contain the patented FruitflowTM
technology. FruitflowTM was developed by Provexis in order to help regular
'healthy' consumers reduce the risk of heart attack and stroke. The natural
bioactive works by reducing blood platelet aggregation ('thinning the blood'), a
significant contributing factor to a thrombosis (internal blood clot). SircoTM
carries the health claim 'Helps to Maintain a Healthy Heart and Benefits
Circulation' and is approved by the leading heart health charity, HEART UK.

Commenting on the expanded distribution, Dr Stephen Franklin, CEO of Provexis,
said:

'We are delighted to have received this substantial increased commitment from
the third major retailer prior to the date of its planned launch. Our focused
media campaign to consumers is scheduled to commence on 21 January 2006 and our
sales support activities have been in effect since 10 January'.


For further information please contact:

Provexis plc
Dr Stephen Franklin                                       020 8392 6631

Bell Pottinger Corporate & Financial
Ann-Marie Wilkinson/Emma Kent                             020 7861 3232



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