Change to Sirco Listings

Provexis PLC
20 April 2006


                                  PROVEXIS PLC
                         ('Provexis' or the 'Company')

                        Change to current Sirco Listings

Provexis, the nutraceutical company that develops scientifically-proven
functional and medical foods, announces that J Sainsbury will de-list SircoTM
from 17 May 2006.

In a quarterly range review, the retailer announced a wide-ranging
rationalisation of chilled juice brands, encompassing both established brands
and some newer products, including Sirco(TM).

This decision by J Sainsbury has no impact on our distribution agreements with
Tesco and Waitrose and Sirco(TM)continues to see an increasing rate of sale in
both the 550 Tesco stores and 120 Waitrose stores in which the product is sold.
Furthermore, the Company is in discussions with other major multiple and high
street retailers to extend distribution of the existing one litre product and
also the forthcoming 250ml single-serving pack.

Commenting on the news, Dr Stephen Franklin said:

'Naturally we are frustrated to lose a customer in the early stages of launch,
whilst we are establishing the brand with consumers via our national marketing
campaign. However, we understand that this decision has been made by J Sainsbury
as a result of the significant rationalisation of its juice category. Our
remaining customer base is extensive and we are increasing the rate of sale at
these stores. In addition, we are progressing discussions with other retailers
in order to increase our distribution within the multiple grocer and health
channels.'


For further information please contact:

Provexis plc
Dr Stephen Franklin                          020 8392 6631

Bell Pottinger Corporate & Financial
Emma Kent/Victoria Geoghegan                 020 7861 3232



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