Result of Equity Issue

Proteome Sciences PLC
19 April 2000


Proteome Sciences plc ('the Company' or 'Proteome')

Results of Open Offer

On 28 March 2000, Proteome announced the terms of a Placing of 3,777,775 new
Ordinary Shares with certain existing shareholders and the terms of an Open
Offer of up to 10,199,636 new Ordinary Shares to qualifying shareholders. 

Proteome announces that in addition to the 3,777,775 new ordinary shares
placed with certain existing shareholders, valid applications have been
received from Qualifying Shareholders for 6,157,268 New Ordinary Shares,
representing 60.3 per cent. of the New Ordinary Shares which were available
for take up under the Open Offer.

Applications received in respect of excess shares will be allocated in full.

The Placing and the Open Offer remain conditional upon admission of the new
Ordinary Shares to trading on AIM and the passing of resolution 1 to be
proposed at the forthcoming Extraordinary General Meeting.

The new Ordinary Shares to be allotted pursuant to the Placing and the Open
Offer are expected to commence trading on AIM at 8.30 a.m. on 25 April 2000.