Holding(s) in Company

Proteome Sciences PLC
06 October 2004



                     Proteome Sciences plc ('the Company')

Proteome Sciences plc was today advised that as at the close of business on 5
October 2004, Man Financial Limited had a notifiable interest in 3,700,500
ordinary shares in the Company, representing 3.02% of its current issued
ordinary share capital.









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