Holding(s) in Company

Proteome Sciences PLC
03 August 2004




                     Proteome Sciences plc ('the Company')


Proteome Sciences plc was today advised that at the close of business on the 2nd
August 2004 Man Financial Limited have a notifiable interest in 5,678,875
ordinary shares in the Company, representing 4.64% of its current issued
ordinary share capital.

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