Holding(s) in Company

Proteome Sciences PLC
02 August 2004


                     Proteome Sciences plc ('the Company')



Proteome Sciences plc was today advised that at the close of business on the
30th July 2004 Man Financial Limited have a notifiable interest in 6,676,375
ordinary shares in the Company, representing 5.45% of its current issued
ordinary share capital.




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