Holding(s) in Company

Proteome Sciences PLC
12 May 2004


                     Proteome Sciences PLC ('the Company')

                               Holding in Company

The Company was yesterday notified by Man Financial Limited that it is the
beneficial owner of 9,048,875 ordinary shares of 1p each ('Ordinary Shares'),
representing approximately 7.5 per cent. of the Company's issued Ordinary Share
capital.


12 May 2004



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