Holding(s) in Company

Proteome Sciences PLC
14 November 2003

Proteome Sciences Plc ('the Company')

NOTIFICATION OF MAJOR INTERESTS IN SHARES

The Company received a notification today from GNI Limited informing it that
they have a beneficial interest in 8,455,375 ordinary shares, representing 7.10
per cent of the issued ordinary share capital of the Company.

14 November 2003




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