Change of Adviser

Proteome Sciences PLC
22 December 2003


                             Proteome Sciences PLC


                  Appointment of Nominated Adviser and Broker



Proteome Sciences PLC is pleased to announce that Evolution Beeson Gregory has
been appointed as its nominated adviser and broker with immediate effect.





22 December 2003


For further information


Christopher Pearce, Proteome Sciences Plc                 01932 865 065
James Malthouse, Proteome Sciences Plc






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