Holding(s) in Company

Prodesse Investment Limited 11 February 2008 TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached : Prodesse Investment Limited 2. Reason for the notification (please state Yes/No): ( ) An acquisition or disposal of voting rights: ( Yes ) An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached: ( No ) An event changing the breakdown of voting rights: ( No ) Other (please specify) : ( No ) 3. Full name of person(s) subject to the notification obligation (iii): Henderson Global Investors Limited 4. Full name of shareholder(s) (if different from 3.) (iv): 5. Date of the transaction (and date on which the threshold is crossed or reached if different) (v): 6. Date on which issuer notified: 08 February 2008 7. Threshold(s) that is/are crossed or reached: Above 5% 8. Notified details: ................. A: Voting rights attached to shares Class/type of shares if Situation previous to the Triggering transaction (vi) possible using the ISIN CODE Number of shares Number of voting Rights (viii) GB00B06FN106 Resulting situation after the triggering transaction (vii) Class/type of shares if Number of Number of voting % of voting possible using the ISIN shares rights (ix) rights CODE Direct Direct (x) Indirect Direct Indirect (xi) 1,428,440 1,428,440 5.07% B: Financial Instruments Resulting situation after the triggering transaction (xii) Type of Expiration Exercise/ Number of voting rights that may % of financial Date Conversion be acquired if the instrument is voting instrument (xiii) Period/ Date exercised/ converted. rights (xiv) Total (A+B) Number of voting rights % of voting right 1,428,440 5.07% 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable (xv): Proxy Voting: 10. Name of the proxy holder: ................. 11. Number of voting rights proxy holder will cease to hold: ................. 12. Date on which proxy holder will cease to hold voting rights: ................. 13. Additional information: ................. 14. Contact name: Vina Patel 15. Contact telephone number: +44 (0) 20 7818 6439 This information is provided by RNS The company news service from the London Stock Exchange
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