Major Interest in Shares

Oxford Biomedica PLC
13 February 2008


For Immediate Release                                           13 February 2008


                                OXFORD BIOMEDICA


               TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached (ii):

Oxford BioMedica PLC


2. Reason for the notification

An acquisition or disposal of voting rights: (Yes)


3. Full name of person(s) subject to the notification obligation (iii):

MF Global UK Limited


4. Full name of shareholder(s) (if different from 3.) (iv):



5. Date of the transaction (and date on which the threshold is crossed or
reached if different) (v):

12 February 2008


6. Date on which issuer notified:

13 February 2008


7. Threshold(s) that is/are crossed or reached:

Below 3%


8. Notified details:

A: Voting rights attached to shares

Class/type of shares Situation previous to the Triggering transaction
if possible using                          (vi)
the ISIN CODE
                      Number of shares  Number of voting Rights (viii)
GB0006648157                18,325,176                      18,325,176


Resulting situation after the triggering transaction (vii)
Class/type of shares  Number of shares    Number of voting       % of voting
if possible using                           rights (ix)            rights
the ISIN CODE
                                Direct Direct (x)    Indirect   Direct Indirect
                                                         (xi)
GB0006648157                  Below 3%   Below 3%             Below 3%


B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of     Expiration Date  Exercise/Conversion Number of voting     % of voting
financial   (xiii)           Period/Date (xiv)   rights that may be   rights
instrument                                       acquired if the
                                                 instrument is
                                                 exercised/
                                                 converted.
N/A                      N/A                 N/A                  N/A              N/A


Total (A+B)
 Number of voting rights  % of voting rights
               7,689,280            Below 3%


9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):



Proxy Voting:

10. Name of the proxy holder:

N/A


11. Number of voting rights proxy holder will cease to hold:

N/A



12. Date on which proxy holder will cease to hold voting rights:

N/A


13. Additional information:

None


14. Contact name:

Andrew Wood


15. Contact telephone number:

01865 783000




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