Holding(s) in Company

Oxford Biomedica PLC
20 March 2007


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
   voting rights are attached (ii):

   Oxford BioMedica PLC

2. Reason for the notification (please state Yes/No): ( )

   An acquisition or disposal of voting rights: (Yes)
   An acquisition or disposal of financial instruments which may result in the
   acquisition of shares already issued to which voting rights are attached: ( )
   An event changing the breakdown of voting rights: ( )
   Other (please specify) : ( )

3. Full name of person(s) subject to the notification obligation (iii):

   Credit Agricole Cheuvreux International Ltd

4. Full name of shareholder(s) (if different from 3.) (iv):

   Credit Agricole Cheuvreux International Ltd
   Credit Agricole Asset Management Group

5. Date of the transaction (and date on which the threshold is crossed or
   reached if different) (v):

   16 March 2007

6. Date on which issuer notified:

   19 March 2007
 
7. Threshold(s) that is/are crossed or reached:

   9% to 8%

8. Notified details:


A: Voting rights attached to shares

Class/type of shares Situation previous to the Triggering transaction (vi)
if possible using                          
the ISIN CODE
                      Number of shares  Number of voting Rights (viii)
GB0006648157                45,663,819                      45,663,819


Resulting situation after the triggering transaction (vii)
Class/type of shares  Number of shares    Number of voting       % of voting
if possible using                           rights (ix)            rights
the ISIN CODE
                                Direct Direct (x)    Indirect   Direct Indirect
                                                         (xi)
GB0006648157                45,463,819 45,463,819                8.52%


B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of     Expiration Date  Exercise/Conversion Number of voting     % of voting
financial   (xiii)           Period/Date (xiv)   rights that may be   rights
instrument                                       acquired if the
                                                 instrument is
                                                 exercised/
                                                 converted.
N/A                    N/A                 N/A                N/A            N/A


Total (A+B)
 Number of voting rights  % of voting rights
              46,463,819               8.52%


9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):
               Registered Holder                            Holding        %

               SAS Rue La Boetie
               Credit Agricole SA
               Calyon SA
               Credit Agricole Cheuvreux SA              44,777,476     8.39
               Credit Agricole Asset Management Group


Proxy Voting:

10. Name of the proxy holder:

    N/A

11. Number of voting rights proxy holder will cease to hold:

    N/A

12. Date on which proxy holder will cease to hold voting rights:

    N/A

13. Additional information:

    None

14. Contact name:

    Andrew Wood

15. Contact telephone number:

    01865 783000


Annex to Notification Of Major Interests In Shares (xvi)


A: Identity of the person or legal entity subject to the notification obligation


Full name (including legal form for legal entities):
Credit Agricole Cheuvreux International Ltd

Contact address (registered office for legal entities):
Broadwalk House, 5 Appold Street, London EC2A 2DA

Phone number:
020 7214 5282

Other useful information (at least legal representative for legal persons):
N/A


B: Identity of the notifier, if applicable (xvii)

Full name:
Karen Browne, Senior Compliance Executive

Contact address:
Calyon Corporate and Investment Bank
Broadwalk House, 5 Appold Street, London EC2A 2DA

Phone number:
020 7214 5282



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