Holding(s) in Company

Oxford Biomedica PLC
16 March 2007


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
   voting rights are attached (ii):

   Oxford BioMedica PLC

2. Reason for the notification (please state Yes/No): ( )

   An acquisition or disposal of voting rights: ()
   An acquisition or disposal of financial instruments which may result in the
   acquisition of shares already issued to which voting rights are attached: ( )
   An event changing the breakdown of voting rights: ( )
   Other (please specify) : (Yes) The Transparency Directive requires a major
                            shareholder to make an announcement by 20 March 2007
                            even though it has not been required to do so 
                            because of an acquisition or disposal of voting 
                            rights or due to a change in the total voting rights
                            in issue.

3. Full name of person(s) subject to the notification obligation (iii):

   UBS Investment Bank

4. Full name of shareholder(s) (if different from 3.) (iv):

   N/A. Note that UBS AG now reports holdings on a disaggregated basis and this
   announcement relates to UBS Investment Bank alone.

5. Date of the transaction (and date on which the threshold is crossed or
   reached if different) (v):

   12 March 2007

6. Date on which issuer notified:

   13 March 2007

7. Threshold(s) that is/are crossed or reached:

   Below 3%

8. Notified details:
  
A: Voting rights attached to shares

Class/type of shares Situation previous to the Triggering transaction (vi)
if possible using                          
the ISIN CODE
                      Number of shares  Number of voting Rights (viii)
GB0006648157                19,832,755                      19,832,755


Resulting situation after the triggering transaction (vii)
Class/type of        Number of shares Number of voting rights     % of voting
shares if possible                              (ix)                rights
using the ISIN CODE
                               Direct     Direct (x)  Indirect   Direct Indirect
                                                          (xi)
GB0006648157           Non-notifiable Non-notifiable         - Below 3%        -


B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of     Expiration Date  Exercise/Conversion Number of voting     % of voting
financial   (xiii)           Period/Date (xiv)   rights that may be   rights
instrument                                       acquired if the
                                                 instrument is
                                                 exercised/
                                                 converted.
-                       -                   -                 -            -


Total (A+B)
 Number of voting rights  % of voting rights
          Non-notifiable            Below 3%


9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):
               Registered Holder                            Holding        %





Proxy Voting:

10. Name of the proxy holder:

    N/A

11. Number of voting rights proxy holder will cease to hold:

    N/A

12. Date on which proxy holder will cease to hold voting rights:

    N/A

13. Additional information:

    This disclosure has been made to fulfil the below FSA requirement:

    The Transparency Directive states that where a major shareholder has not been
    required (because of an acquisition or disposal of voting rights or due to a
    change in the total voting rights in issue) to make an announcement to the
    issuer prior to 20 March 2007, then they must do so by that date in any event.

14. Contact name:

    Angela Huff
    Associate Director, UBS AG

15. Contact telephone number:

    020 7568 4981



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