Holding(s) in Company

Oxford Biomedica PLC
22 April 2005


Oxford BioMedica plc (the 'Company')

Notification of Major Interests in Shares

The Company has received notification today from Calyon Corporate and Investment
Bank that Credit Agricole Cheuvreux International Ltd has an interest in
29,962,000 Oxford BioMedica plc 1p ordinary shares. This represents 8.00% of the
presently issued share capital of the Company, which stands at 374,756,353
shares.

Andrew Wood
Chief Financial Officer
Tel [phone]



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