Holding(s) in Company

Oxford Biomedica PLC
27 April 2005


Oxford BioMedica plc (the 'Company')

Notification of Major Interests in Shares

The Company has received notification today from Man Financial Limited that on
26 April 2005 it was the beneficial owner of 30,345,600 Oxford BioMedica plc 1p
ordinary shares. This represents 8.10% of the presently issued share capital of
the Company, which stands at 374,806,728 shares.

27 April 2005

Andrew Wood
Chief Financial Officer
Tel. [phone]



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