Holding(s) in Company

Oxford Biomedica PLC
31 January 2005


Oxford BioMedica plc (the 'Company')

Notification of Major Interests in Shares

The Company has received notification from Calyon Corporate and Investment Bank
that on 28 January 2005, Credit Agricole Cheuvreux International Ltd had an
interest in 26,802,000 Oxford BioMedica plc 1p ordinary shares. This represents
7.19% of the presently issued share capital of the Company, which stands at
372,841,990 shares.

Andrew Wood
Chief Financial Officer
Tel [phone]



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