Holding(s) in Company

Oxford Biomedica PLC
19 February 2008


For Immediate Release                                        19 February 2008


                              Oxford Biomedica Plc

                TR-1: Notifications of Major Interests in Shares

                            

1. Identity of the issuer or the underlying issuer of existing shares to which 
voting rights are attached:

Oxford Biomedica Plc

2. Reason for notification (yes/no)


An acquisition or disposal of voting rights                               Yes

An acquisition or disposal of financial instruments which may result in
the acquisition of shares already issued to which voting rights are
attached

An event changing the breakdown of voting rights

Other (please specify):
Credit Agricole Cheuvreux International Ltd

3. Full name of person(s) subject to notification obligation:

Credit Agricole Cheuvreux International Ltd
CAAM

4. Full name of shareholder(s) (if different from 3):

11/02/08

5. Date of transaction (and date on which the threshold is crossed or reached if
different):

3/02/08

6. Date on which issuer notified:
3%

7. Threshold(s) that is/are crossed or
reached:

8: Notified Details
A: Voting rights attached to shares

Class/type of Situation previous to Resulting situation after the triggering
shares        the triggering        transaction
              transaction
If possible
use ISIN code

              Number of  Number of  Number of   Number of voting      Percentage of
              shares     voting     shares      rights                voting rights
                         rights


                                                            Indirect  Direct  Indirect


GB0006648157  39,885,886 39,885,886 20,575,630  20,575,630            3.83%





Total (A+B)

Number of voting rights                Percentage of voting rights

20,575,630                             3.83%


9. Chain of controlled undertakings through which the voting rights and /or
the financial instruments are effectively held, if applicable:

SAS Rue La Boetie

Credit Agricole SA

Calyon SA

CAAM

Credit Agricole Cheuvreux SA 19,889,287 3.7%

13. Additional information:

14 Contact name:                       Anne McLeod

15. Contact telephone name:            0207 214 6518






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