Holding(s) in Company

Oxford Biomedica PLC
03 August 2007


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached (ii):

Oxford BioMedica PLC


2. Reason for the notification (please state Yes/No): ( )

An acquisition or disposal of voting rights: (Yes)

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached: ( )

An event changing the breakdown of voting rights: ( )

Other (please specify) : ( )


3. Full name of person(s) subject to the notification obligation (iii):

MF Global UK Limited


4. Full name of shareholder(s) (if different from 3.) (iv):



5. Date of the transaction (and date on which the threshold is crossed or
reached if different) (v):

2 August 2007


6. Date on which issuer notified:

3 August 2007


7. Threshold(s) that is/are crossed or reached:

3%


8. Notified details:

3.85%


A: Voting rights attached to shares

Class/type of shares if possible using Situation previous to the Triggering transaction
the ISIN CODE                                                (vi)
                                        Number of shares  Number of voting Rights (viii)

GB0006648157                                    Below 3%                        Below 3%


Resulting situation after the triggering transaction (vii)
Class/type of shares if        Number of shares Number of voting rights (ix)  % of voting rights
possible using the ISIN
CODE
                                         Direct    Direct (x)  Indirect (xi)     Direct   Indirect

GB0006648157                         20,592,634    20,592,634                     3.85%


B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of        Expiration Date (    Exercise/Conversion      Number of voting rights   % of voting rights
financial      xiii)                Period/Date (xiv)        that may be acquired if
instrument                                                   the instrument is
                                                             exercised/ converted.

N/A                             N/A                      N/A                       N/A                  N/A


Total (A+B)
    Number of voting rights     % of voting rights


                 20,592,634                  3.85%


9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):



Proxy Voting:

10. Name of the proxy holder:

N/A


11. Number of voting rights proxy holder will cease to hold:

N/A



12. Date on which proxy holder will cease to hold voting rights:

N/A


13. Additional information:

None


14. Contact name:

Andrew Wood


15. Contact telephone number:

01865 783000


Annex to Notification Of Major Interests In Shares (xvi)


A: Identity of the person or legal entity subject to the notification obligation


Full name (including legal form for legal entities):

MF Global UK Limited


Contact address (registered office for legal entities):


Phone number:


Other useful information (at least legal representative for legal persons):



B: Identity of the notifier, if applicable (xvii)


Full name:

Contact address:


Phone number:




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