Holding(s) in Company

Oxford Biomedica PLC
02 August 2007


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached (ii):

Oxford BioMedica PLC


2. Reason for the notification (please state Yes/No): ( )

An acquisition or disposal of voting rights: (Yes)

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached: ( )

An event changing the breakdown of voting rights: ( )

Other (please specify) : ( )


3. Full name of person(s) subject to the notification obligation (iii):

Man Financial Limited


4. Full name of shareholder(s) (if different from 3.) (iv):



5. Date of the transaction (and date on which the threshold is crossed or
reached if different) (v):

1 August 2007


6. Date on which issuer notified:

2 August 2007


7. Threshold(s) that is/are crossed or reached:

3% to 2%


8. Notified details:

Below 3%


A: Voting rights attached to shares

Class/type of shares if possible using Situation previous to the Triggering transaction
the ISIN CODE                                                (vi)
                                        Number of shares  Number of voting Rights (viii)

GB0006648157                                  21,070,855                      21,070,855


Resulting situation after the triggering transaction (vii)
Class/type of shares if        Number of shares Number of voting rights (ix)  % of voting rights
possible using the ISIN
CODE
                                         Direct    Direct (x)  Indirect (xi)     Direct   Indirect

GB0006648157                           Below 3%      Below 3%                  Below 3%


B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of        Expiration Date (    Exercise/Conversion      Number of voting rights   % of voting rights
financial      xiii)                Period/Date (xiv)        that may be acquired if
instrument                                                   the instrument is
                                                             exercised/ converted.

N/A                             N/A                      N/A                       N/A                  N/A


Total (A+B)
 Number of voting rights     % of voting rights

                 15,634,634               Below 3%


9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):



Proxy Voting:

10. Name of the proxy holder:

N/A


11. Number of voting rights proxy holder will cease to hold:

N/A



12. Date on which proxy holder will cease to hold voting rights:

N/A


13. Additional information:

None


14. Contact name:

Andrew Wood


15. Contact telephone number:

01865 783000






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