Holding(s) in Company

Oxford Biomedica PLC
28 September 2005


Oxford BioMedica plc (the 'Company')

Notification of Major Interests in Shares

The Company received notification on 27 September 2005 from Legal & General
Investment Management that Legal & General Group plc and/or its subsidiaries had
an interest in 11,941,885 Oxford BioMedica plc 1p ordinary shares. This
represents 3.16% of the presently issued share capital of the Company, which
stands at 377,737,898 shares.

28 September 2005

Andrew Wood
Chief Financial Officer
Tel. [phone]



                      This information is provided by RNS
            The company news service from the London Stock Exchange