Holding(s) in Company

Oxford Biomedica PLC
19 December 2005


                      Oxford BioMedica plc (the 'Company')


                              Holdings in Company



The Company was notified on 16 December 2005 by M&G Investment that as at the 
close of business on 15 December 2005, it held an aggregate interest in 
39,400,734 ordinary shares of 1p each ('Ordinary Shares'), representing 
approximately 7.75 per cent. of the Company's issued Ordinary Share capital.

This holding is registered as follows:

Registered Holder                          Holding of         Percentage                                             
                                           Ordinary Shares    Holding (%)  
Prudential plc                             19,700,367         3.87
The Prudential Assurance Company Limited   19,700,367         3.87

                                   Total   39,400,734         7.75




19 December 2005






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