Holding(s) in Company

Oxford Biomedica PLC
02 September 2004


                                  SCHEDULE 10
                   NOTIFICATION OF MAJOR INTERESTS IN SHARES

 1.  Name of company
     Oxford BioMedica Plc

 2.  Name of shareholder having a major interest
     Man Financial Limited

 3.  Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18.
     As above

 4.  Name of the registered holder(s) and, if more than one holder, the number
     of shares held by each of them
     Not disclosed

 5.  Number of shares/amount of stock acquired
     Not disclosed

 6.  Percentage of issued class
     N/A

 7.  Number of shares/amount of stock disposed
     Not disclosed

 8.  Percentage of issued class
     N/A

 9.  Class of security
     Ordinary shares

10.  Date of transaction
     NOT DISCLOSED

11.  Date company informed
     1st September 2004

12.  Total holding following this notification
     29,485,600 shares

13.  Total percentage holding of issued class following this notification
     7.93%

14.  Any additional information

15.  Name of contact and telephone number for queries
     Andrew Wood 01865 783000

16.  Name and signature of authorised company official responsible for making
     this notification.
     Andrew Wood CFO Oxford BioMedica

Date of notification: 2 September 2004




                      This information is provided by RNS
            The company news service from the London Stock Exchange