Holding(s) in Company

Oxford Biomedica PLC
22 September 2004


Oxford BioMedica plc (the 'Company')

Notification of Major Interests in Shares

The Company has received a notification from Calyon Corporate and Investment
Bank on 22 September 2004 on behalf of Credit Agricole Cheuvreux International
Ltd, informing it that they have an interest in 25,102,000 shares representing
6.75% of the issued share capital of the Company, which currently stands at
371,961,736 shares.

Andrew Wood
Chief Financial Officer
Tel [phone]



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