Holding(s) in Company

Oxford Biomedica PLC
17 September 2004

Oxford BioMedica plc (the 'Company')

Notification of Major Interests in Shares

The Company has received two notifications from Calyon Corporate and Investment
Bank on 16 & 17 September 2004 on behalf of Credit Agricole Cheuvreux
International Ltd.

The first informing it that they have an interest in 18,702,000 shares
representing 5.03% of the issued share capital and the second informing it that
they now have and interest in 18,552,000 shares representing 4.99% of the issued
shares capital of the Company which currently stands at 371,961,736 shares.

Andrew Wood
Chief Financial Officer
Tel [phone]



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