Holding(s) in Company

Oxford Biomedica PLC
20 February 2004

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1.       Name of company

         Oxford BioMedica Plc

2.       Name of shareholder having a major interest

         GNI Limited

3.       Please state whether notification indicates that it is in respect of holding of the shareholder
         named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder
         if it is a holding of that person's spouse or children under the age of 18.

         As above

4.       Name of the registered holder(s) and, if more than one holder, the number of shares held by each
         of them

         Not disclosed

5.       Number of shares/amount of stock acquired

         Not disclosed

6.       Percentage of issued class

         Not disclosed

7.       Number of shares/amount of stock disposed

         Not disclosed

8.       Percentage of issued class

         Not disclosed

9.       Class of security

         Ordinary shares of 1 pence each

10.      Date of transaction

         19 February 2004

11.      Date company informed

         20 February 2004

12.      Total holding following this notification

         40,866,598

13.      Total percentage holding of issued class following this notification

         11.02%

14.      Any additional information

15.      Name of contact and telephone number for queries
          Andrew Wood , Chief Financial Officer , 01865 783000

          Date of notification  20 February 2004
16.      Name and signature of authorised company official responsible for making this notification.

         Andrew Wood CFO Oxford BioMedica



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