Holding(s) in Company

Oxford Biomedica PLC
10 November 2003


                           SCHEDULE 10
 
             NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF COMPANY
     OXFORD BIOMEDICA PLC


2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST
     GNI LIMITED


3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18
     AS ABOVE


4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.
     NOT DISCLOSED


5)   Number of shares/amount of stock acquired.
     NOT DISCLOSED


6)   Percentage of issued Class
     NOT DISCLOSED

7)   Number of shares/amount of stock disposed
     NOT DISCLOSED

8)   Percentage of issued Class
     NOT DISCLOSED

9)   Class of security
     ORDINARY SHARES OF 1 PENCE EACH


10)  Date of transaction
     NOT DISCLOSED


11)  Date company informed
     10 NOVEMBER 2003


12)  Total holding following this notification
     30,094,598

               
13)  Total percentage holding of issued class following this notification
     8.13%


14)  Any additional information
     


15)  Name of contact and telephone number for queries
     ANDREW WOOD 01865 783000


16)  Name and signature of authorised company official responsible for 
     making this notification
     
     Date of Notification
     10 NOVEMBER 2003


                      This information is provided by RNS
            The company news service from the London Stock Exchange