Holding(s) in Company

Oxford Biomedica PLC
29 October 2003

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1.       Name of company

          Oxford BioMedica Plc

2.       Name of shareholder having a major interest

         GNI Limited

3.       Please state whether notification indicates that it is in respect of holding of the shareholder
         named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder
         if it is a holding of that person's spouse or children under the age of 18.

         As above

4.       Name of the registered holder(s) and, if more than one holder, the number of shares held by each
         of them

          Not disclosed

5.       Number of shares/amount of stock acquired

         Not disclosed

6.       Percentage of issued class

         N/A

7.       Number of shares/amount of stock disposed

         N/A

8.       Percentage of issued class

         N/A

9.       Class of security

         Ordinary shares of 1 pence each

10.      Date of transaction

         27th October 2003

11.      Date company informed

         28th October 2003

12.      Total holding following this notification

         27,684,598

13.      Total percentage holding of issued class following this notification

         7.48

14.      Any additional information

          Notification required as a result of the completion of rights issue

15.      Name of contact and telephone number for queries

         Andrew Wood 01865 783000

16.      Name and signature of authorised company official responsible for making this notification.

         Andrew Wood CFO Oxford BioMedica

Date of notification: 29th October 2003





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