Directors' Dealings

Oxford Biomedica PLC
8 March 2000

                   Oxford BioMedica plc ('the Company')

                            Directors Dealings

Following significant demand for the Company's shares certain of the directors
sold ordinary shares in the Company yesterday and today at an average price of
110.75p. The dealings and resultant holdings are as follows:

Name                  No. of Shares Sold      Residual Amount    Residual
                                                                 Percentage of
                                                                 issued capital

Alan Kingsman                    500,000           9,442,000*       6.05
Susan Kingsman                   500,000           9,592,000*       6.15
Alan Goodman**                 1,000,000           5,058,000        3.24

* This amount includes 210,000 shares held jointly between Alan and Susan
Kingsman

** The interest of Alan Goodman includes 4,980,000 ordinary shares held by a
company of which Alan Goodman is a controlling shareholder.