Slimbiome study results

RNS Number : 9655S
OptiBiotix Health PLC
15 March 2023
 

OptiBiotix Health plc

("OptiBiotix" or the "Company" or the "Group")

 

SlimBiome ® human study results

Shows SlimBiome ® reduces hunger and food cravings

 

OptiBiotix Health plc (AIM: OPTI), a life sciences business developing compounds to tackle obesity, high cholesterol, diabetes and skincare,announces that it has completed a third human study on SlimBiome®.

 

The study followed recommended industry guidelines and was designed to investigate the impact of a single dose of SlimBiome® in the presence of 50g sugar (12 teaspoons) on 20 healthy volunteers on their glycaemic response, hunger, and cravings. Blood samples were obtained at 0 (fasting), 15, 30, 45, 60, 75, 90, 120 and 150min post intervention intake.  Feelings of hunger, fullness, desire to eat, and amount of food desired were assessed at 0, 75 and 150min using the visual analogue scale, a questionnaire used in nutrition research to assess appetite and food intake .

 

The results showed that when compared to sugar alone, volunteers taking SlimBiome® experienced significant changes to important appetite and hunger regulation parameters including:-

 

· a statistically significant reduction (15.4%) in the insulin response (p=0.02)

· statistically significant reduced feelings of hunger compared to sugar (p=0.038)

· statistically significant greater feelings of fullness compared to sugar (p=0.021)

· trend for lower desire to eat compared to sugar.

 

No safety, compliance, or tolerance issues were reported by volunteers. The results of this study provide further evidence of the ability of a single dose of SlimBiome® to moderate the impact of the ingestion of a large amount of sugar by reducing the insulin response.  A reduced insulin response has been correlated with increased satiety or fullness.  The results from the visual analogue questionnaire supported this correlation with volunteers taking SlimBiome® showing significant reductions in hunger, increased fullness, and a reduced desire to eat.  The results are consistent with consumer feedback and customer product reviews who report feeling less hungry leading to reduced snacking and lower food intake leading to an average weight loss of 1.2kg per week.

 

These findings show SlimBiome® can have a role as a functional ingredient by itself as in SlimBiome Medical®, in meal replacements as in GoFigure®, or as part of a healthy snack in controlling hunger and desire to eat as part of a calorie controlled diet.

 

 

Stephen O'Hara, CEO of OptiBiotix, commented: " The recent approval of the injectable drug semaglutide by NICE has generated pharmaceutical and consumer interest in products which can have an impact on weight management by helping users reduce hunger and food cravings with sales forecast to reach $3.69bn by 20251. This recent study on SlimBiome ® is one of three independent human studies which all show an ability to reduce hunger and food cravings leading to a reduction in food intake and weight loss. This effect is similar to that attributed to semaglutide, albeit by a different mechanism, and opens up opportunities for pharma companies looking to market similar non-invasive OTC products.

"This new approach to weight loss, given greater prominence by approval of drugs like semaglutide, suggest that h unger free dieting is now a consumer choice and that the use of SlimBiome® by itself or its incorporation into food or snack products can help customers manage weight loss by reducing food intake without hunger and food cravings." 

1 Novo Nordisk eyes obesity sales of $3.7bn in 2025 thanks to Wegovy | pharmaphorum

 

For further information, please contact:

 

OptiBiotix Health plc

www.optibiotix.com

Neil Davidson, Chairman

Contact via Walbrook below

Stephen O'Hara, Chief Executive


 

 

Cenkos Securities plc ( Joint Broker)

Tel: 020 7397 8900

Callum Davidson


Michael Johnson / Russell Kerr (Sales)


 


Peterhouse Capital Limited (Joint Broker)

Tel: 020 7220 9797

Duncan Vasey/ Lucy Williams




Walbrook PR Ltd

Mob: 07876 741 001

Anna Dunphy


 

 

This communication is a "Reach" announcement. Reach is a non-regulatory news service. By using this service an issuer is confirming that the information contained in this announcement is of a non-regulatory nature. Information required to be notified under the AIM Rules for Companies, Market Abuse Regulation or other regulation would be disseminated as an RNS regulatory announcement and not on RNS Reach.

This information is provided by Reach, the non-regulatory press release distribution service of RNS, part of the London Stock Exchange. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

Reach is a non-regulatory news service. By using this service an issuer is confirming that the information contained within this announcement is of a non-regulatory nature. Reach announcements are identified with an orange label and the word “Reach” in the source column of the News Explorer pages of London Stock Exchange’s website so that they are distinguished from the RNS UK regulatory service. Other vendors subscribing for Reach press releases may use a different method to distinguish Reach announcements from UK regulatory news.

RNS may use your IP address to confirm compliance with the terms and conditions, to analyse how you engage with the information contained in this communication, and to share such analysis on an anonymised basis with others as part of our commercial services. For further information about how RNS and the London Stock Exchange use the personal data you provide us, please see our Privacy Policy.
 
END
 
 
NRAJIMFTMTABBFJ
UK 100

Latest directors dealings