Change of Registered Office

Evolutec Group PLC
25 April 2005


For immediate release                                             25 April 2005


                               EVOLUTEC GROUP PLC
                         ('Evolutec' or 'the Company')

                          Change of Registered Office

Evolutec Group plc (AIM: EVC), the biopharmaceutical company developing novel
products for the treatment of allergic, inflammatory and autoimmune diseases, is
pleased to announce that the address of the Company's registered and head office
has changed to:

250 South Oak Way, Green Park, Reading, Berkshire RG2 6UG.

Mark Carnegie Brown, Evolutec's Chief Executive, said: 'This move to larger
premises highlights the continuing development of the Company. In addition,
Reading offers excellent transport links both to London and internationally via
Heathrow Airport.'

                                      ENDS

For further information:


Evolutec                                                           0118 922 4480
Mark Carnegie Brown, Chief Executive Officer
Nicholas Badman, Chief Financial Officer
www.evolutec.co.uk

Collins Stewart                                                    020 7523 8350
Chris Howard

Buchanan Communications                                            020 7466 5000
Mark Court/Tim Anderson/Mary-Jane Johnson

Notes for Editors:

About Evolutec

Evolutec, which is based in Reading, UK, is a clinical stage biopharmaceutical
company with a focus on allergy, inflammation and auto-immune diseases.

The Company has commenced a 112 patient proof of concept Phase II clinical
trial with rEV131, its lead product, in allergic rhinitis.  Evolutec intends to
carry out additional proof of concept Phase II trials with rEV131 in
post-cataract surgery and dry eye.  Positive pre-clinical data has also been
generated in asthma.  rEV131 is a histamine binding protein and is understood to
be the only product currently in clinical trials that impacts the recently
discovered H4 receptor, a receptor implicated in many forms of inflammatory
disease.

The Company has a further two products in pre-clinical development: rEV598,
which is being evaluated in carcinoid syndrome and CINV (chemotherapy-induced
nausea and vomiting), and rEV576, a complement inhibitor.

Evolutec was founded in 1998 to exploit research carried out by the Natural
Environment Research Council.  Evolutec's drugs were first isolated from the
saliva of ticks. The tick remains undetected by its hosts, including humans, by
injecting an array of molecules into the skin that suppresses normal defence
mechanisms.  These stealth molecules have evolved over millions of years to
enable the tick to take a blood meal from its host. Evolutec employs the tick's
evolutionary stealth technology to offer the potential of treating human
diseases.

Safe Harbour statement: this news release may contain forward-looking statements
that reflect the current expectations of the Company regarding future events.
Forward-looking statements involve risks and uncertainties. Actual events could
differ materially from those projected herein and depend on a number of factors
including the success of the Company's research strategies, the applicability of
the discoveries made therein, the successful and timely completion of clinical
studies, the uncertainties related to the regulatory process, the successful
integration of completed mergers and acquisitions and achievement of expected
synergies from such transactions, and the ability of the Company to identify and
consummate suitable strategic and business combination transactions.




                      This information is provided by RNS
            The company news service from the London Stock Exchange