Holding(s) in Company

Phytopharm PLC
7 March 2005

Re: Disclosure of interests in shares

In accordance with Section 198-202 of the UK Companies Act 1985, HBOS plc
informed us on 7th March 2005 that it and its subsidiary companies have a
notifiable interest in 2,701,463 ordinary shares of Phytopharm plc, amounting
to 4.81%, on the basis of Phytopharm's current issued share capital of
43,099,700 ordinary shares.

Registered Holder:                       Fund:        Number of     Percentage  
                                                    Shares Held:     Holding: 

HSDL Nominees Limited                     N/A                36         0.00% 
State Street Nominees Limited a/c 2GEH   2GEH            40,596         0.09%  
State Street Nominees Limited a/c 2GDX   2GDX            46,839         0.11% 
State Street Nominees Limited a/c 2GEG   2GEG           340,079         0.79% 
State Street Nominees Limited a/c 2GDW   2GDW           443,539         1.03%  
State Street Nominees Limited a/c 2GDS   2GDS         1,200,374         2.79%   

Aggregate material Holding of HBOS Group              2,071,463         4.81% 
 
 

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