Holding(s) in Company

Phytopharm PLC 14 April 2008 TR-1: notification of major interests in shares 1. Identity of the issuer or the underlying Phytopharm plc issuer of existing shares to which voting rights are attached: 2. Reason for the notification (please tick the appropriate box or boxes) An acquisition or disposal of voting rights YES An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Other (please specify): Placing 3. Full name of person(s) subject to the Gartmore Investment Limited notification obligation: 4. Full name of shareholder(s) (if different See attached schedule from 3.): 5. Date of the transaction (and date on which 28/03/08 the threshold is crossed or reached if different) 6. Date on which issuer notified: 09/04/08 7. Threshold(s) that is/are crossed or reached: 5% 8. Notified details: A: Voting rights attached to shares Class/type Situation previous Resulting situation after the triggering of shares to the Triggering transaction transaction if possible using the Number Number of Number of Number of voting % of voting ISIN CODE of Voting shares rights rights Shares Rights Direct Direct Indirect xi Direct Indirect x Ordinary 1 Pence Nil Nil 5,293,784 Nil 5,293,784 Nil 5.599% GB000686972 B: Financial Instruments Resulting situation after the triggering transaction Type of Expiration Exercise/ Number of voting rights that may % of financial date Conversion be acquired if the instrument is voting instrument Period/ Date exercised/ converted. rights Total (A+B) Number of voting rights % of voting rights 5,293,784 5.599% 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: Name of the Company/Fund Number of Shares % of issued share capital Gartmore Fund Managers Ltd A/C Gartmore UK & Irish Smaller Companies 1,527,308 1.615% Indirect Gartmore Investment Limited - Gartmore Fledgling Trust plc 2,391,900 2.530% Indirect Gartmore Investment Limited - Strathclyde Pension Fund 1,374,576 1.454% Indirect Total direct Nil Nil Total Indirect 5,293,784 5.599% Total 5,293,784 5.599% Proxy Voting: 10. Name of the proxy holder: 11. Number of voting rights proxy holder will cease to hold: 12. Date on which proxy holder will cease to hold voting rights: 13. Additional Notification using the total voting rights figure of information: 94,544,038 14. Contact name: Zoe McGowan, Company Secretary 15. Contact telephone number: 01480 437697 This information is provided by RNS The company news service from the London Stock Exchange

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