Holding(s) in Company

Phytopharm PLC
04 April 2008




TR-1:    NOTIFICATION OF MAJOR INTERESTS IN SHARES 


1. Identity of the issuer or the underlying                 Phytopharm plc
issuer of existing shares to which voting rights        
are attached:


2. Reason for the notification (please tick the appropriate box or
boxes)                                                                      

An acquisition or disposal of voting rights                      YES

An acquisition or disposal of financial instruments which may result in      
the acquisition of shares already issued to which voting rights are       
attached

An event changing the breakdown of voting rights                             
                            
Other (please specify): Placing                                              
                              

3. Full name of person(s) subject to the                  Mr Klaus Hebben
notification obligation:                                


4. Full name of shareholder(s) (if different                    N/A
from 3.):                                               


5. Date of the transaction (and date on which                 28/03/08
the threshold is crossed or reached if                  
different)


6. Date on which issuer notified:                             02/04/08

                        
7. Threshold(s) that is/are crossed or reached:                 10%

                                
8. Notified details:


A: Voting rights attached to shares

Class/type  Situation previous to the Resulting situation after the triggering
of shares   Triggering transaction    transaction

if possible
using the   Number of  Number of  Number of  Number of voting    % of voting
ISIN CODE   Shares     Voting     shares     rights              rights
                       Rights     Direct     Direct Indirect xi  Direct Indirect
                                                   x
Ordinary 1
Pence       5,307,000  5,307,000  9,852,454   Nil     9,852,454   Nil    10.42%
GB000686972





B: Financial Instruments

Resulting situation after the triggering transaction

Type of     Expiration Exercise/     Number of voting rights that may   % of
financial   date       Conversion    be acquired if the instrument is   voting
instrument             Period/ Date  exercised/ converted.              rights





Total (A+B)

Number of voting rights                      % of voting rights

9,852,454                                    10.42%



9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:




Proxy Voting:


10. Name of the proxy holder:



11. Number of voting rights proxy holder will cease to hold:



12. Date on which proxy holder will cease to hold voting rights:



13. Additional    Notification using the total voting rights figure of
information:      94,544,038
                  Holding includes shares held by Estatecord Limited (formerly
                  included within the interest of Chakra Limited).



14. Contact name: Zoe McGowan, Company Secretary




15. Contact telephone number:     01480 437697




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