Director Shareholding

Phytopharm PLC 10 December 2001 DEALINGS BY DIRECTORS 1) NAME OF COMPANY PHYTOPHARM PLC 2) NAME OF DIRECTOR Ms J E ALLAN 3) Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person's spouse or children under the age of 18 or in respect of an non-beneficial interest AS 2 4) Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them. (If notified) AS 2 5) Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s) DIRECTOR ONLY 6) Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary EXERCISE OF OPTION AND MARKET SALE 7) Number of shares/amount of stock acquired 77489 8) (0.20%) of issued Class 9) Number of shares/amount of stock disposed 77,489 10) (0.20%) of issued Class 11) Class of security ORDINARY 12) Price per share NO. BOUGHT SOLD 43,489 £0.45 £5.20 34,000 £1.925 £5.45 13) Date of transaction 7 DEC 01 10 DEC 01 14) Date company informed 10 DEC 01 15) Total holding following this notification NIL 16) Total percentage holding of issued class following this notification NIL IF A DIRECTOR HAS BEEN GRANTED OPTIONS BY THE COMPANY PLEASE COMPLETE THE FOLLOWING BOXES 17) Date of grant 18) Period during which or date on which exercisable 19) Total amount paid (if any) for grant of the option 20) Description of shares or debentures involved: class, number. 21) Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise 22) Total number of shares or debentures over which options held following this notification 23) Any additional information 24) Name of contact and telephone number for queries 25) Name and signature of authorised company official responsible for making this notification Date of Notification 10 DEC 2001

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