Director/PDMR Shareholding

Phytopharm PLC
06 August 2007


NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL
RESPONSIBILITY OR CONNECTED PERSONS

This form is intended for use by an issuer to make a RIS notification required
by DR 3.1.4R(1.

(1)     An issuer making a notification in respect of a transaction relating to
shares or debentures of the issuer should complete boxes 1 to 16, 23 and 24.

(2)     An issuer making a notification in respect of a derivative relating to
the shares of the issuer should complete boxes 1 to 4, 6, 8, 13, 14, 16, 23 and
24.

(3)     An issuer making a notification in respect of options granted to a
director/person discharging managerial responsibilities should complete boxes 1
to 3 and 17 to 24.

(4)     An issuer making a notification in respect of a financial instrument
relating to the shares of the issuer (other than a debenture) should complete
boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24.


Please complete all relevant boxes in block capital letters.

  1.  Name of the issuer                   2.  State whether the notification
                                               relates to (i) a transaction
                                               notified in accordance with DR
                                               3.1.4R(1)(a); or

      PHYTOPHARM PLC                           (ii) DR 3.1.4(R)(1)(b) a
                                               disclosure made in accordance
                                               with section 324 (as extended by
                                               section 328) of the Companies Act
                                               1985; or

                                               (iii) both (i) and (ii)

                                               NOTIFICATION RELATES TO (iii)

  3.  Name of person discharging           4.  State whether notification
      managerial responsibilities/             relates to a person connected
      director                                 with a person discharging
                                               managerial responsibilities/
                                               director named in 3 and identify
                                               the connected person

      DR DARYL REES                            AS 3 ABOVE

  5.  Indicate whether the notification    6.  Description of shares (including
      is in respect of a holding of the        class), debentures or derivatives
      person referred to in 3 or 4 or in       or financial instruments relating
      respect of a non-beneficial              to shares
      interest

      AS 3 ABOVE                               OPTIONS OVER ORDINARY SHARES OF 1
                                               PENCE EACH

  7.  Name of registered shareholder(s)    8.  State the nature of the
      and, if more than one, the number        transaction
      of shares held by each of them

  9.  Number of shares, debentures or     10.  Percentage of issued class
      financial instruments relating to        acquired (treasury shares of that
      shares acquired                          class should not be taken into
                                               account when calculating
                                               percentage)

 11.  Number of shares, debentures or     12.  Percentage of issued class
      financial instruments relating to        disposed (treasury shares of that
      shares disposed                          class should not be taken into
                                               account when calculating
                                               percentage)

 13.  Price per share or value of         14.  Date and place of transaction
      transaction

 15.  Total holding following             16.  Date issuer informed of
      notification and total percentage        transaction
      holding following notification
      (treasury shares of that class
      should not be taken into account
      when calculating percentage)

If a person discharging managerial responsibilities has been granted options by
the issuer complete the following boxes

 17.  Date of grant                                   18.  Period during which
                                                           or date on which it
                                                           can be exercised

      3 AUGUST 2007                                        3 AUGUST 2009 TO 
                                                           2 AUGUST 2017

 19.  Total amount paid (if any) for grant of the     20.  Description of shares
      option                                               or debentures
                                                           involved (class and
                                                           number)

      NIL                                                  908,974 PHYTOPHARM
                                                           PLC ORDINARY 1 PENCE
                                                           SHARES

 21.  Exercise price (if fixed at the time of grant)  22.  Total number of
      or indication that price is to be fixed at the       shares or debentures
      time of exercise                                     over which options
                                                           held following
                                                           notification

      EXERCISE PRICE FOR 712,949 SHARES FORTY FOUR         1,258,974
      AND ONE HALF PENCE PER SHARE

      EXERCISE PRICE FOR 196,025 SHARES ONE PENCE
      PER SHARE

 23.  Any additional information                      24.  Name of contact and
                                                           telephone number for
                                                           queries

      DR REES HAS SURRENDERED 712,949 OPTIONS              ZOE MCGOWAN
      GRANTED AT MARKET VALUE UNDER PREVIOUS COMPANY       01480 437697
      PLANS FOR AN OPTION FOR 712,949 SHARES UNDER
      THE PHYTOPHARM SHARE OPTION PLAN 2007. DR REES
      HAS SURRENDERED A FURTHER 106,025 OPTIONS
      GRANTED AT ONE PENCE FOR AN OPTION FOR 106,025
      SHARES UNDER THE PHYTOPHARM LONG TERM
      INCENTIVE PLAN 2007.

      DR REES HAS BEEN GRANTED AN ADDITIONAL OPTION        
      OVER 90,000 SHARES UNDER THE PHYTOPHARM LONG
      TERM INCENTIVE PLAN 2007

      THE OPTIONS ARE SUBJECT TO PERFORMANCE
      CONDITIONS MEASURING THE COMPANY'S TOTAL
      SHAREHOLDER RETURN (TSR) AGAINST THE TSR OF
      THE FTSE SMALLCAP INDEX COMMENCING ON THE
      GRANT DATE.



Name and signature of duly authorised officer of issuer responsible for making
notification

___ZOE MCGOWAN_________________________________________________________

Date of notification _6 AUGUST 2007____________________________________
                             




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