Blocklisting Interim Review

Phytopharm PLC
18 September 2007


                        BLOCK LISTING SIX MONTHLY RETURN


Information provided on this form must be typed or printed electronically.


To: The FSA


Date: 18 September 2007

Name of applicant:                        Phytopharm plc

Name of scheme:                           The Phytopharm 1996 Unapproved
                                          Discretionary Share Option Scheme

Period of return:              From:  17 March 2007   To:  16 September 2007

Balance under scheme from previous        140,712 Ordinary shares of 1 pence
return:

The amount by which the block scheme has  Nil
been increased, if the scheme has been
increased since the date of the last
return:

Number of securities issued/allotted      Nil
under scheme during period:

Balance under scheme not yet issued/      140,712 Ordinary shares of 1 pence
allotted at end of period

Number and class of securities originally 400,000 Ordinary Shares of 1 pence
listed and the date of admission

Total number of securities in issue at    55,606,309 Ordinary Shares of 1 Pence
the end of the period

Name of contact:       Zoe McGowan

Address of contact:    Corpus Christi House, 9 West Street, Godmanchester

Telephone number of
contact:               01480 437697


SIGNED BY Zoe McGowan

Company Secretary,

for and on behalf of


___Phytopharm plc____________________________________________


If you knowingly or recklessly give false or misleading information you may be
liable to prosecution.



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