Portfolio Valuation

Intl. Biotechnology Trust PLC 8 November 2000 International Biotechnology Trust plc Basis of Portfolio Valuation Since its launch in 1994, IBT has valued all quoted investments at mid market price. Henceforth, the Company will adopt the industry standard BVCA valuation on quoted securities upon which there are contractual restrictions in dealing. The immediate impact will be that provisions will be made against certain investments and result in a reduction in the net asset value of approximately 5%. As and when the restrictions are removed, the provisions will be released. The majority of the restrictions on the current portfolio will have expired by mid 2001. ENQUIRIES International Biotechnology Trust Dennis Turner 020 7831 311 Merrill Lynch Melville Trimble 020 7772 1000 Financial Dynamics David Yates 020 7831 3113
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