Portfolio Update

Intl. Biotechnology Trust PLC
04 December 2006


          FOR IMMEDIATE RELEASE                                        04-Dec-06


            To : The London Stock Exchange


International Biotechnology Trust plc

The Board of International Biotechnology Trust plc announces that the top ten
investments as at Thursday 30 November 2006  were as follows:


            NAME % of Gross Assets

            Top 10 Investments

            Progenics Pharmaceuticals               3.76

            Noven Pharmaceuticals                   3.50

            GPC Biotech                             3.47

            Shire                                   3.30

            Alexion                                 3.21

            PowderMed                               3.11

            Tanox                                   3.07

            CSL                                     3.04

            Gilead Sciences                         2.80

            GTx                                     2.79


By Order of the Board
Schroder Investment Management Limited
Secretaries


Enquiries :

International Biotechnology Trust plc                 Tina Watts   020 7658 3953


                      This information is provided by RNS
            The company news service from the London Stock Exchange