Portfolio Update

Intl. Biotechnology Trust PLC
04 September 2007





                     International Biotechnology Trust plc




The Board of International Biotechnology Trust plc announces that the top ten
holdings as a percentage of net assets at Friday 31 August 2007 are:




MGI Pharma Com                                                           3.73
CSL                                                                      3.58
Gen Probe Com                                                            3.54
Celgene Com                                                              3.50
Gilhead Sciences Com                                                     3.45
Inverness Medical Innovation Com                                         3.38
Pharmacopeia Drug Discovery Com                                          3.29
GTx Com                                                                  3.18
EV3 Com                                                                  3.15
Morphsys NPV                                                             3.06





                             By Order of the Board

                     Schroder Investment Management Limited

                               Company Secretary






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Enquiries :

International Biotechnology Trust plc

Tina Watts 020 7658 3581


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