Holding(s) in Company

Intl. Biotechnology Trust PLC
06 June 2003


                                                                     6 June 2003




                    Substantial Share Interest Notification




We are writing to advise you that the Company was notified on 5 June 2003, that,
following a sale of 1,000,000 ordinary shares on 4 June 2003, the Co-operative
Insurance Society Limited holds as beneficial owner 4,636,467 ordinary shares of
25p each in the Company, representing 9.64% of the 48,115,467 ordinary shares in
issue.






Enquiries:

John Spedding

Schroder Investment Management Limited          Tel: [phone]


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