Holding in Company

Intl. Biotechnology Trust PLC 24 January 2001 LETTER TO: COMPANY ANNOUNCEMENTS OFFICE SUBSTANTIAL SHARE INTEREST NOTIFICATION We are writing to advise you that the Company was notified on 24 January 2001, that Prudential Plc has a notifiable interest in 2,518,024 ordinary shares of 25p each in the Company, representing 5.18% of the 48,615,467 ordinary shares in issue. LETTER FROM: INTERNATIONAL BIOTECHNOLOGY TRUST PLC
UK 100

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