Holding in Company

Intl. Biotechnology Trust PLC 24 January 2001 LETTER TO COMPANY ANNOUNCEMENTS OFFICE SUBSTANTIAL SHARE INTEREST NOTIFICATION We are writing to advise you that the Company was notified on 24 January 2001, that following acceptance of the Company's Tender Offer, Millennium Partners LP has ceased to have an interest the issued share capital of the Company. FROM SCHRODER INVESTMENT MANAGEMENT LIMITED
UK 100

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